Neuroscience News
Does Alzheimer's start outside the brain? Gladstone Institutes researchers mapped the first atlas of 92 blood proteins that cross the blood-brain barrier, discovering that the barrier shuts down the import of protective liver proteins before it ever begins leaking toxins.
Brain disorders
Neuroscience News
Meet the brain's trash compactor: UVA Health researchers discovered that the CASS4 risk gene directs microglia to tightly pack and contain toxic amyloid plaques, proving Alzheimer's risk operates directly through immune defenses rather than neurons.
Brain disorders
Neuroscience News
Can an infection in youth seed Alzheimer's in old age? FAU and TUM scientists investigate a "cellular long-term memory" in neurons and microglia, where damaged long-lived RNA molecules leave brain cells primed for neurodegenerative collapse.
Brain disorders
ScienceDaily
A surprising new study suggests that an anti-aging drug could help protect people genetically predisposed to Alzheimer's disease. Researchers found that just four weeks of low-dose rapamycin improved brain blood flow in healthy middle-aged adults carrying the high-risk APOE4 gene variant, with women showing the strongest benefits. Because declining blood flow can occur years before Alzheimer's symptoms appear, the…
Brain disorders
ScienceDaily
A surprising new study suggests that eating peanuts every day could help support brain health and memory in older adults. Researchers found that consuming about two servings of unsalted, skin-roasted peanuts daily for 16 weeks improved insulin responsiveness in brain regions important for memory, a function that often weakens with age and has been linked to Alzheimer's disease.
Memory and learning
ScienceDaily
A surprising two-year clinical trial found that fish oil supplements successfully delivered omega-3s to the brain but failed to improve memory or protect against Alzheimer's-related brain shrinkage. Researchers suspect that getting these nutrients through a healthy diet may offer benefits that supplements alone cannot provide.
Memory and learning
ScienceDaily
Walking just 3,000 steps a day could help slow Alzheimer’s-related brain changes, according to new research. Scientists discovered that physical activity was linked to less buildup of harmful tau proteins and nearly half the cognitive and functional decline, even in people already showing early signs of the disease. The strongest benefits appeared at 5,000 to 7,500 daily steps, suggesting that the popular…
Brain disorders
ScienceDaily
For decades, scientists have focused on amyloid beta as a major culprit behind Alzheimer’s disease, spending billions of dollars developing treatments that have often delivered disappointing results. Now, researchers at UC Santa Cruz are drawing attention to a largely overlooked peptide called P3 that could also play a role in the disease. Previously believed to be harmless, P3 can form harmful-looking protein…
Brain disorders
